Our lab had a well deserved summer break – Go karting, team bonding & partying with lots of beer, pizza & sunshine.

garden

gokart

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Latest paper has just been published in Nature Catalysis

The Micklefield Lab’s latest paper has just been published in Nature Catalysis. The paper describes the discovery of a new biosynthetic pathway, with a highly unusual carboxylase enzyme (MloH), producing a structurally unique antibiotic malonomycin. The new findings might lead to the discovery of new antibiotics and may also provide new ways of making antibiotics which are urgently needed to combat emerging drug-resistant pathogens.

http://dx.doi.org/10.1038/s41929-018-0178-2

https://rdcu.be/bbZ99

https://go.nature.com/2r4Smbu

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Visiting Professorship at the East China University of Science and Technology

Jason Micklefield received a Visiting Professorship at the East China University of Science and Technology from Professor Yingping Zhuang the Dean of the Faculty of Bioengineering. He will use the position to consolidate collaborations with Professor Lixin Zhang’s group at ECUST and other laboratories in China.Visiting prof

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Dr Imtiaz Khan

We are pleased to welcome Dr Imtiaz Khan into the Micklefield Lab. Imtiaz will be working on a new BBSRC funded project, integrating enzymes with chemocatalysts to open up new reaction pathways, following on from early work in the lab – https://www.nature.com/articles/ncomms11873
Micklefield Lab intercat

 

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Structure and Biocatalytic Scope of Coclaurine N‐Methyltransferase

Micklefield lab paper published online – Structure and Biocatalytic Scope of Coclaurine N‐Methyltransferase – Angewandte Chemie International Edition – Wiley Online Library https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201805060#.WztyyOva6SU.twitter …

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New publication – De novo Biosynthesis of “Non‐Natural” Thaxtomin Phytotoxins

De novo Biosynthesis of “Non‐Natural” Thaxtomin Phytotoxins – Winn – 2018 – Angewandte Chemie International Edition – Wiley Online Library https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201801525#.WzJHxI2Z8OY.twitter

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Congratulations to Dr. Jean-Marc Henry

We would like to congratulate Jean-Marc on obtaining his Ph.D.

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Congratulations to Dr. Daniel Francis

We would like to congratulate Dan on obtaining his Ph.D.

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Congratulations to Dr. Victoria Cronin

We would like to congratulate Vicki on obtaining her Ph.D

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Congratulations to Dr. Heidi Fisk

We would like to congratulate Heidi on obtaining her Ph.D.

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