Micklefield Lab


Role: Professor of Chemical Biology


Email: jason.micklefield@manchester.ac.uk

Tel: 0161 306-4509

Twitter: @Micklefield_Lab

Manchester Institute of Biotechnology – 2.017
Department of Chemistry
The University of Manchester
131 Princess Street
M1 7DN




Jason Micklefield is Professor of Chemical Biology within the School of Chemistry and the Manchester Institute of Biotechnology. He graduated from the University of Cambridge in 1993 with a PhD in Chemistry, working with Prof Sir Alan R. Battersby FRS to complete the first total synthesis of haem d1. He then moved to the University of Washington, USA, as a NATO postdoctoral fellow investigating various biosynthetic pathways and enzyme mechanisms with Prof Heinz G. Floss. In 1995 he began his independent research career as a Lecturer in Organic Chemistry at Birkbeck CollegeUniversity of London before moving to Manchester in 1998.

Current Research

The Micklefield lab is engaged in Chemical Biology and Synthetic Biology research tackling diverse challenges at the Chemistry-Biology interface utilising techniques and knowledge from organic chemistry and enzymology through to molecular microbiology and genetics. The main research themes include: 1) Biosynthesis and biosynthetic pathway engineering; 2) Biocatalysis and enzyme mechanism; 3) Nucleic acid redesign and recognition (Riboswitches).

Selected Publications

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