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Our latest paper just out in Nature Chemical Biology describes highly unexpected cryptic enzymology, not seen before in nature, and provides a new way to synthesise peptides (future therapeutics) using ligase enzymes. Cryptic enzymatic assembly of peptides armed with β-lactone … Continue reading →

Sydney, Izzy, Guangcai, Puja, Waraporn and Elsa from our lab had a great time at Directing Biosynthesis #DBVII. Some fantastic lectures including a super talk from Guangcai on the cryptic enzymatic assembly of peptide anticancer agents. Many thanks to the … Continue reading →

Beautiful first day for our lab retreat, visiting Grasmere, Rydal Caves and even warm enough for a swim Day 2 of our visit to the lakes we trekked to the summit of Silver How before heading down to Grasmere It … Continue reading →

Very happy our lab was awarded an ERC Advanced Grant. We will be looking to recruit several postdocs and PhDs soon 🙂 https://erc.europa.eu/news-events/news/erc-2023-advanced-grants-results https://www.manchester.ac.uk/discover/news/manchester-researchers-awarded-prestigious-funding-to-pursue-projects-that-could-lead-to-major-scientific-breakthroughs/

The Micklefield lab have been awarded the Royal Society of Chemistry’s 2023 Chemistry Biology Interface Horizon Prize: Rita and John Cornforth Award, in collaboration with GlaxoSmithKline, for successfully discovered new enzymes for sustainable synthesis. They discovered and engineered enzymes and pathways … Continue reading →

Our lab had its annual summer party. Lots of beer & food as usual. It was great fun even when it started raining and we had to pack into the front room. Well done for all your excellent research. It … Continue reading →

We are having a great time at Directing Biosynthesis VI in Edinburgh presenting our recent research and enjoying some fantastic talks including an excellent lecture from our very own Wei li Thong

Want to see what a typical day in our lab looks like. Meet members of our group having fun, planning, executing and presenting their exciting research!

Prof Dongxu Jia studied for his PhD at Jiangnan University in the field of fermentation engineering. He now works at the Zhejiang University of Technology as an associate professor and joins us as a visiting researcher with a CSC fellowship … Continue reading →

Aimee received her MChem degree from the University of Manchester. Continuing in Manchester, Aimee joined the iCAT CDT. She has previously completed project rotations with the Procter and the Bures group Kehan studied for an MChem in Chemistry at the … Continue reading →