Dr. Jordi Morral Cardoner

Jordi gained his PhD at the University de Barcelona and became a PDRA at Leuven and Antwerp in Belgium. Following on from working at the Micklefield lab, Jordi moved on to become a lecturer in Pharmaceutical Chemistry at the University of Huddersfield, and an associate lecturer with the Open University.


Mixed-sequence pyrrolidine-amide oligonucleotide mimics: Boc(Z) synthesis and DNA/RNA binding properties. R. Worthington, A. O’Rourke, J. Morral, T.H.S. Tan and J. Micklefield Org. Biomol. Chem., 2007, 5, 249-259. (http://dx.doi.org/10.1039/b613386j)

Homopolymeric pyrrolidine-amide oligonucleotide mimics: Fmoc-synthesis and DNA/RNA binding properties. T.H.S. Tan, R. Worthington, A. O’Rourke, J. Morral, R.G. Pritchard and J. Micklefield Org. Biomol. Chem., 2007, 5, 239-248. (http://dx.doi.org/10.1039/b613384n)

These two OBC papers were highlighted on the front cover: “Pyrrolidine amide oligonucleotide mimics (POM): Chemical biology solutions from zebrafish developmental biology through to high throughput DNA sequencing.”

Superior nucleic acid binding properties of adeninyl pyrrolidine-amide oligonucleotide mimics (POM). T.H.S. Tan, D.T. Hickman, J. Morral, I.G. Beadham and J. Micklefield Chem. Commun. 2004, 516-517. (http://dx.doi.org/10.1039/b315768g)

Design, synthesis, conformational analysis and nucleic acic hybridisation properties of thymidyl pyrrolidine-amid oligonuceotide mimics (POM). D.T. Hickman, T.H.S. Tan, J. Morral, P.M. King, M.A. Cooper and J. Micklefield Org. Biomol. Chem. 2003, 1, 3277-3292. (http://dx.doi.org/10.1039/b306156f)

Conference contributions, refereed:

A.P. O’Rourke, R.J. Worthington, J. Morral and J. Micklefield “Synthesis and UV hybridization studies of mixed-sequence pyrrolidine-amide oligonucleotide mimics (POM).” Abstr. Pap. Am. Chem. Soc. 2005, 230, ORGN-605.

A.I. Khan, T.H.S. Tan, J. Morral-Cardoner and J. Micklefield “Synthesis and DNA/RNA binding properties of conformationally restricted pyrrolidine-amide oligonucleotide mimics (POM).” Abstr. Pap. Am. Chem. Soc. 2003, 226, ORGN-510.

Conference contributions, other (presenting author is underlined):

T.H.S. TanJ. Morral-Cardoner, D.T. Hickman and J. Micklefield. “Solid phase synthesis and biophysical studies of pyrrolidine-amide oligonucleotide mimics (POM).” IUPAC 6th International Symposium of Bio-organic Chemistry, Toronto, Canada, Aug 11-14, 2002, pp. 75.