Dr Luis Bering

Luis received his Bachelor’s (2012) and his Master’s (2014) degree in Chemical Biology from the TU Dortmund University, Germany. In 2019, he completed his doctoral studies with the highest distinction (summa cum laude) under the supervision of Prof. Dr. Andrey P. Antonchick at the Max Planck Institute of Molecular Physiology (Dortmund, Germany) where he was working on different approaches for the functionalization of unreactive C–H bonds under metal-free reaction conditions. Luis joined the Micklefield group in 2019 as a postdoctoral research fellow, funded by the German Research Foundation (DFG). His research interest covers different approaches for combining chemo- and biocatalysis enabling improved and more sustainable telescoping routes to pharmaceuticals and other important molecules.

Outside the lab, Luis likes hiking, board games and a cold beer.


Publication List

11. Merging Enzymes with Chemocatalysis for Sustainable Amide Bond Synthesis. L. Bering, E. J. Craven, S. A. Sowerby Thomas, S. Shepherd & Jason Micklefield submitted manuscript, 2021.

10. Discovery, characterization and engineering of ligases for amide synthesis. M. Winn, M. Rowlinson, F. Wang, L. Bering, D. Francis, C. Levy & J. Micklefield Nature, 2021, 593, 391–398. (https://doi.org/10.1038/s41586-021-03447-w)

9. Reactive nitrogen species: nitrosonium ions in organic synthesis. L. Bering & A. P. Antonchick Tetrahedron, 2019, 75, 1131-1143 (invited mini-review). (https://doi.org/10.1016/j.tet.2019.01.036)

8. Nitrosonium ion catalysis: aerobic, metal-free cross-dehydrogenative carbon–heteroatom bond formation. L. Bering, L. D’Ottavio, G. Sirvinskaite, & A. P. Antonchick Chem. Commun. 2018, 54, 13022-13025. (https://doi.org/10.1039/C8CC08328B)

7. Oxidative Heteroatom–Heteroatom Bond Formation. L. Bering & A. P. Antonchick Patai’s Chemistry of Functional Groups, John Wiley & Sons, Ltd: Chichester, UK, 2018. (invited book chapter). (https://doi.org/10.1002/9780470682531.pat0946)

6. Selective, Catalytic, and Metal-Free Coupling of Electron-Rich Phenols and Anilides Using Molecular Oxygen as Terminal Oxidant. L. Bering, M. Vogt, F. M. Paulussen & A. P. Antonchick Org. Lett. 2018, 20, 4077–4080. (https://doi.org/10.1021/acs.orglett.8b01631)

5. Metal-Free C–O Bond Functionalization: Catalytic Intramolecular and Intermolecular Benzylation of Arenes. L. Bering, K. Jeyakumar & A. P. Antonchick Org. Lett. 2018, 20, 3911–3914. (https://doi.org/10.1021/acs.orglett.8b01495)

4. Aerobic, Metal-Free, and Catalytic Dehydrogenative Coupling of Heterocycles: En Route to Hedgehog Signaling Pathway Inhibitors. L. Bering, F. M. Paulussen & A. P. Antonchick Org. Lett. 2018, 20, 1978–1981. (https://doi.org/10.1021/acs.orglett.8b00521)

3. Sustainable, Oxidative, and Metal-Free Annulation. L. Bering, S. Manna & A. P. Antonchick Chem. Eur. J. 2017, 23, 10936–10946 (https://doi.org/10.1002/chem.201702063)

2. Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons. L. Bering & A. P. Antonchick Chem. Sci. 2017, 8, 452–457. (https://doi.org/10.1039/C6SC03055F)

1. Regioselective Metal-Free Cross-Coupling of Quinoline N-Oxides with Boronic Acids. L. Bering & A. P. Antonchick Org. Lett. 2015, 17, 3134–3137. (https://doi.org/10.1021/acs.orglett.5b01456)



Mycobacterium-Tuberculosis-Thioredoxin-Reductase Inhibitors as Anti-Tuberculotics. L. Bering & O. Koch WO2019007710, PCT/EP2018/066768, 22.06.2018.