Dr. Mark Goodall

Mark Goodall obtained his BSc. in Chemistry from The University of Manchester in 2008. After graduation, he remained at The University of Manchester and worked towards a PhD in biological chemistry under the supervision of Professor Jason Micklefield. His PhD research was in the area of enzyme catalysis, centring on the chemistry of aryl malonate decarboxylase enzymes and their substrates.

Publications:

Enzymatic Enantioselective Decarboxylative Protonation of Heteroaryl Malonates. R. Lewin, M. Goodall, M.L. Thompson, J. Leigh, M. Breuer, K. Baldenius and J. Micklefield Chem. Eur. J., 2015, 17, 6557-6563. DOI: 10.1002/chem.201406014

Thermal Bifunctionality of Bacterial Phenylalanine Aminomutase and Ammonia Lyase Enzymes. C. Chesters, M. Wilding, M. Goodall and J. Micklefield, Angew. Chem. Int. Ed., 201251, 4344-4348  (http://dx.doi.org/10.1002/anie.201200669)

Decarboxylases: Enzymatic Enantioselective Decarboxylative Protonation and C-C Bond Formation. M. Wilding, M. Goodall and J. Micklefield. Comprehensive Chirality, Elsevier, 2012.

Structure-Guided Directed Evolution of Alkenyl and Arylmalonate Decarboxylases. K. Okrasa, C. Levy, M. Wilding, M. Goodall, N. Baudendistel, B. Hauer, D. Leys and J. Micklefield Angew. Chem. Int. Ed., 200948, 7691-7694. (http://dx.doi.org/10.1002/anie.200904112)

Edited book chapters

M.Wilding, M. Goodall and J. Micklefield “Decarboxylases: Enzymatic enantioselective decarboxylative protonation and C-C bond formation” in Comprehensive Chirality, H.Yamamoto & E. Carreira (Eds.), Elsevier, 2012, vol 7, pp. 402-409. (ISBN 978-0-08-095168-3). (http://dx.doi.org/10.1016/B978-0-08-095167-6.00724-2)