Dr. Neil Dixon

Neil completed his BSc & PhD at the University of Leeds.

Publications:

Dual transcriptional-translational cascade permits cellular level tuneable expression control. R. Morra, J. Shankar, C.J. Robinson, L. Butler, S. Halliwell, S. Hay, J. Micklefield, N. Dixon Nucleic Acid Res. 2016, 44, e21 (http://dx.doi.org/10.1093/nar/gkv912)

Rational Re-engineering of the Transcriptional Silencing PreQ1 Riboswitch. M.-C. Wu, P.T. Lowe, C.J. Robinson, H.A. Vincent, N. Dixon, J. Leigh, J. Micklefield J. Am. Chem. Soc. 2015 137, 9015-9021 (http://dx.doi.org/10.1021/jacs.5b03405) 

Orthogonal Riboswitches for tuneable co-expression in bacteria. N. Dixon, C. Robinson, J.N. Duncan, T. Geerlings, S.P. Drummons and J. Micklefield Angew. Chem. INt. Ed. 2012, 51, 3620-3624. (http://dx.doi.org/10.1002/anie.201109106)

Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues. L. Chen, E. Cressina, N. Dixon, K. Erixon, K. Agyei-Owusu, J. Micklefield, A.G. Smith, C. Abell and F.J. Leeper Org. Biomol. Chem. 2012, 10, 5924-5931. DOI: 10.1039/c2ob07116a

Reengineering orthogonally selective riboswitches. N.Dixon, J. Duncan, T. Geerlings, M.S. Dunstan, D. Leys and J. Micklefield Proc. Natl. Acad. Sci. USA 2010, 107, 2830-2835. (http://dx.doi.org/10.1073/pnas.0911209107). Highlighted in Nature 2010, 463, 591, spotlight in ACS Chemical Biology 2010, 5, 349 and evaluated by Faculty1000.

Cellular targets of natural products. N. Dixon, L.S. Wong, T. Geerlings and J. Micklefield Nat. Prod. Rep 2007, 24, 1288-1310. Highlighted on front cover. (http://dx.doi.org/10.1039/b616808f)

Patents:

N. Dixon and J. Micklefield “Riboswitch-regulated transgene expression systems” PCT INt. Appl. (2012), WO 2012153142. A2 20121115

Conference contributions, refereed

Orthogonal riboswitches as tools for controlling gene expression in bacteria. N. Dixon, C.J. Robinson, J.N. Duncan, T. Geerlings, S.A. Lestari, J. Micklefield, Collection Symposium Series (2011), 12 (Chemistry of Nucleic Acid Components), 86-94

Conference contributions, other (presenting author is underlined

C.J. Robinson, N. Dixon, J.N. Duncan, T. Geerlings, M.-C. Wu, P. Lowe, J. Micklefields, “Orthogonal Riboswitches As Tools for Controlling Gene Expression in Bacteria,” RNA 2012: The 17th Annual Meeting of the RNA Society, The University of Michigan, Ann Arbor, Mi, USA. May 29-Jun 2, 2012

N. Dixon, J. Micklefield et al. Lecture at the 10th Annual RiboClub Meeting Sherbrooke, Canada 21-24th September 2009. New riboswitch-based tools for orthogonal genetic regulation

N. Dixon, J. Micklefield et al. Lecture & poster at the 13th Asian Chemical Congress Shanghai, China 14-16th September 2009. New riboswitch-based tools for orthogonal genetic regulation

N. Dixon, J. Micklefield et al. Lecture at the Nucleic Acid-Chemical Biology Interface Meeting (Royal Society of Chemistry) 7-8th September 2009. New riboswitch-based tools for orthogonal genetic regulation

N. Dixon, J. Micklefield et al. FEBS Advanced Lecture Course. Spetses, Greece, September 2008. Evolution vs. Design: New riboswitch based genetic circuitry.

N. Dixon, J. Micklefield et al. Lecture at the Nucleic Acid Group Meeting (RSC) Southampton July 2008. New riboswitch based genetic circuitry.

N. Dixon, J. Micklefield et al. Lecture at the BBSRC Selective Chemical Intervention in Biological Systems Conference Series October 2007. Co-evolution of small molecule responsive riboswitches.