Gabriel achieved his PhD in Nigeria. He became a PDRA at the University of Strathclyde. He moved on to a PDRA position at the University of Leeds.
Publications:
Active-site modifications of adenylation domains leads to hydrolysis of upstream nonribosomal peptidyl thioester intermediates. G.C. Uguru, C. Milne, M. Borg, F. Flett, C.P. Smith and J. Micklefield J. Am. chem. Soc. 2004, 126, 5032-5033. (http://dx.doi.org/10.1021/ja048778y)
Conference contributions, refereed:
C.E. Milne, Z. Hojati, L. Gordon, J. Jim, G. Uguru, C.P. Smith and J. Micklefield “Structure, biosynthetic origin and engineered biosynthesis of Calcium Dependent Antibiotic from Streptomyces Coelicolor” Abstr. Pap. Am. Chem. Soc. 2003, 226, ORGN-534.
Conference contributions, other (presenting author is underlined):
C. Milne, L. Gordon, Z. hojati, J. Jim, G. Uguru, C.P. Smith and J. Micklefield. “Structure, biosynthetic origin and engineered biosynthesis of calcium dependent antibiotics from Streptomyces Coelicolor.” RSC Postgraduate Symposium on Organic and Medicinal Chemistry, Cambridge University, 9 Dec 2002. (oral/abstract).
C. Milne, L. Gordon, Z. hojati, J. Jim, G. Uguru, C.P. Smith and J. Micklefield. “Structure, biosynthetic origin and engineered biosynthesis of calcium dependent antibiotics from Streptomyces Coelicolor.” RSC Bio-organic Symposium, St. Johns College, Cambridge, 27 Nov 2002. (oral/abstract).
G. Uguru, F. Flett, J. Micklefield, C.P. Smith. “Alteration of the Adenylation domain specificities of CDA NRPS by site-directed mutagenesis” Abstracts of the 9th International Symposium on the genetics of industrial microorganisms (GIM), Gyongju, Korea, 1-5 July, 2002 pp.98
J. Micklefield, A.E. Hayes, Z. H. Najafabadi, G.C. Uguru, J.M. Neary, C. Milne, L. Gordon, J. Jim, M. Borg, F. Flett and C.P. Smith. “CDA biosynthesis: towards the engineered biosynthesis of novel lipopeptide antibiotics.” BBSRC Workshop on Natural Products Biology, University of Warwick, 21-22 May 2001 (poster)
J. Micklefield, A.E. Hayes, Z. H. Najafabadi, G.C. Uguru, J.M. Neary, C. Milne, L. Gordon, J. Jim, M. Borg, F. Flett and C.P. Smith. “Characterisation of the nonribosomal peptide synthetases and other key enzymes involved in CDA biosynthesis: Towards the engineered biosynthesis of novel lipopeptide antibiotics.” Conference on Streptomyces, University of Warwick, Feb 2001. (Poster).