Publications:
Auxotrophic-precursor directed biosynthesis of nonribosomal lipopeptides with modified tryptophan residues. B. Amir-Heidari, J. Thirlway, and J. Micklefield Org. Biomol. Chem. 2008, 6, 975-978. Highlighted on the front cover. (http://dx.doi.org/10.1039/b718766c)
Engineered biosynthesis of nonribosomal lipopeptide antibiotics with modified fatty acid side chains. A. Powell, M. Borg, B. Amir-Heidari, J.M. Neary, J. Thirlway, B. Wilkinson, C.P. Smith and J. Micklefield J. Am. Chem. Soc. 2007, 129, 15182-15191. Articles based on this paper were published in the Daily Express, Chemistry & Industry, Manchester Evening News see below. (http://dx.doi.org/10.1021/ja074331o)
NMR conformation that tryptophan dehydrogenation occurs with syn-stereochemistry during the biosynthesis of CDA in Streptomyces coelicolor. B.A. Heidari and J. Micklefield J. Org. Chem. 2007, 72, 8950-8953. (http://dx.doi.org/10.1021/jo701660v)
Stereochemical course of tryptophan dehydrogenation during calcium-dependent lipopeptide antibiotic biosynthesis. B.A. Heidari, J. Thirlway and J. Micklefield Org. Lett. 2007, 9, 1513-1516. (http://dx.doi.org/10.1021/ol0701619)