Dr. Binuraj Menon

Binuraj completed his M.Sc. & M. Tech in India and his PhD at the University of Manchester. He is currently a PDRA at the University of Manchester

 

Publications:

  • Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase. M. R. Bennett, M. L. Thompson, S. A. Shepherd, M. S. Dunstan, A. J. Herbert, D. R. M. Smith, V. A. Cronin, B. R. K. Menon, C. Levy & J. Micklefield Angew. Chem. Int. Ed. 2018 in press. (http://dx.doi.org/10.1002/anie.201805060)
  • Development of Halogenase Enzymes for Use in Synthesis J. Latham, E. Brandenburger, S. A. Shepherd, B. R. K. Menon and J.Micklefield Chem. Rev 2018, 118, 232-269;  (http://dx.doi.org/10.1021/acs.chemrev.7b00032)
  • RadH: A Versatile Halogenase for Integration into Synthetic Pathways. B. R. K. Menon, E. Brandenburger, H. H. Sharif, U. Klemstein, M. F. Greaney, and J. Micklefield Angew. Chem. Int. Ed. 2017 in press (http://dx.doi.org/10.1002/anie.201706342)
  • Development of Halogenase Enzymes for use in Synthesis. Jonathan Latham, Eileen Brandenburger, Sarah A. Shepherd, Binuraj R. K. Menon and Jason Micklefield. American Chemical Society. 2017, (DOI: 10.1021/acs.chemrev.7b00032)
  • Structure and Biocatalytic Scope of Thermophillic Flavin-Dependent Halogenase and Flavin Reductase Enzymes B. R. K. Menon, J. Latham, M. S. Dunstan, E. Brandenburger, U. Klemstein, S. A. Shepherd, C. Karthikeyan, M. F. Greaney, D. Leys and J. Micklefield* Org. Biomol. Chem. 2016, 14, 9354–9361. (http://dx.doi.org/10.1039/C6OB01861K)
  • Integrated Catalysis Opens New Arylation Pathways via Regiodivergent Enzymatic C-H Activation. J. Latham, J.-M. Henry, H. H. Sharif, B. R. K. Menon, S. A. Shepherd,  M. F. Greaney, J.Micklefield. Nature Commun. 2016, 7, 11873 (http://dx.doi.org/10.1038/NCOMMS11873)
  • A Structure-Guided Switch in the Regioselectivity of a Tryptophan Halogenase. S. A. Shepherd, B. R. K. Menon, H. Fisk, A.-W. Struck, C. Levy, D. Leys, J. Micklefield ChemBioChem 2016, 17, 9, p. 821–824  (http://dx.doi.org/10.1002/cbic.201600051)
  • Extending the Biocatalytic Scope of Regiocomplementary Flavin-Dependent Halogenase Enzymes. S.A. Shepherd, C. Karthikeyan, J. Latham, A.-W. Struck, M. L. Thompson, B. Menon, C. Levy, D. Leys and J. Micklefield Chemical Science 2015, 6, 3454-3460 (http://dx.doi.org/10.1039/C5SC00913H)