Publications:
De novo Biosynthesis of ‘Non-Natural’ Thaxtomin Phytotoxins. M. Winn, D. Francis & J. Micklefield Angew. Chem. Int. Ed. 2018 , in press. (http://dx.doi.org/10.1002/anie.201801525)
An Engineered Tryptophan Synthase Opens New Enzymatic Pathways to β-Methyltryptophan and Derivatives. Daniel Francis, Michael Winn, Jonathan Latham, Michael F Greaney and Jason Micklefield ChemBioChem. 2017 (http://dx.doi.org/10.1002/cbic.201600471)
Recent Advances in Engineering Non-Ribosomal Peptide Assembly Lines. M. Winn, J. Fyans, Y. Zhou, J. Micklefield Nat. Prod. Rep.2016, 33, 317-347 (http://dx.doi.org/10.1039/C5NP00099H)
Functional exchangeability of oxidase and dehydrogenase reactions in the biosynthesis of hydroxyphenylglycine, a non-ribosomal peptide building block. V. Diez, M. Loznik, S. Taylor, M. Winn, N.J.W. Rattray, H. Podmore, J. Micklefield, R. Goodacre, M.H. Medema, U. Müller, R. Bovenberg, D.B. Janssen and E. Takano. ACS Synthetic Biology 2015, 4, 796-807. DOI:10.1021/sb500368w