Our latest paper just out in Nature Chemical Biology describes highly unexpected cryptic enzymology, not seen before in nature, and provides a new way to synthesise peptides (future therapeutics) using ligase enzymes.<\/p>\n
Cryptic enzymatic assembly of peptides armed with \u03b2-lactone warheads.\u00a0Nature Chem Biol\u00a0(2024): https:\/\/doi.org\/10.1038\/s41589-024-01657-7<\/a><\/p>\n A Research Briefing “Enzymatic synthesis of peptide therapeutics”\u00a0 includes a summary of the results, author insight, along with opinions from the reviewer and editors: https:\/\/doi.org\/10.1038\/s41589-024-01658-6<\/a><\/p>\n This blog provides further insight into the discovery “Elucidating how nature installs reactive warheads onto peptides<\/a>.\u201d<\/p>\n For more news commentary read, “Manchester scientists pave way for greener cancer treatments with new enzyme discovery<\/a>“<\/p>\n","protected":false},"excerpt":{"rendered":" Our latest paper just out in Nature Chemical Biology describes highly unexpected cryptic enzymology, not seen before in nature, and provides a new way to synthesise peptides (future therapeutics) using ligase enzymes. Cryptic enzymatic assembly of peptides armed with \u03b2-lactone … Continue reading