{"id":1342,"date":"2021-06-11T16:51:02","date_gmt":"2021-06-11T15:51:02","guid":{"rendered":"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?p=1342"},"modified":"2021-06-11T16:59:42","modified_gmt":"2021-06-11T15:59:42","slug":"our-labs-latest-paper-is-in-nature","status":"publish","type":"post","link":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?p=1342","title":{"rendered":"Our labs latest paper is in Nature."},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/wp-content\/uploads\/2021\/06\/Image-copy.jpg\" width=\"589\" height=\"221\" \/><\/p>\n<p>The paper is about amide ligase enzymes &#8211; from bacterial phytotoxins, natural product biosynthesis, enzyme structure &amp; engineering, to biocatalysis &amp; new routes to drugs for COVID19 etc.<br class=\"\" \/><br class=\"\" \/><a href=\"https:\/\/www.nature.com\/articles\/s41586-021-03447-w\">https:\/\/www.nature.com\/articles\/s41586-021-03447-w<\/a><br class=\"\" \/><a href=\"https:\/\/rdcu.be\/ckWgF\">https:\/\/rdcu.be\/ckWgF<\/a><\/p>\n<p>For more information see the<a href=\"https:\/\/www.manchester.ac.uk\/discover\/news\/manchester-scientists-accelerate-path-for-covid-19-drug-development\/\"> full news story here<\/a>.<\/p>\n<p>For more technical details behind the paper see this <a href=\"https:\/\/chemistrycommunity.nature.com\/posts\/discovery-characterization-and-engineering-of-ligases-for-amide-synthesis?channel_id=1465-behind-the-paper\">blog pos<\/a><a href=\"https:\/\/chemistrycommunity.nature.com\/posts\/programmable-late-stage-c-h-bond-functionalization-enabled-by-integration-of-enzymes-with-chemocatalysis\">t<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The paper is about amide ligase enzymes &#8211; from bacterial phytotoxins, natural product biosynthesis, enzyme structure &amp; engineering, to biocatalysis &amp; new routes to drugs for COVID19 etc.https:\/\/www.nature.com\/articles\/s41586-021-03447-whttps:\/\/rdcu.be\/ckWgF For more information see the full news story here. For more technical &hellip; <a href=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?p=1342\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":10,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1342","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/posts\/1342","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/10"}],"replies":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1342"}],"version-history":[{"count":3,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/posts\/1342\/revisions"}],"predecessor-version":[{"id":1352,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/posts\/1342\/revisions\/1352"}],"wp:attachment":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1342"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1342"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1342"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}