{"id":1071,"date":"2018-11-30T11:12:27","date_gmt":"2018-11-30T11:12:27","guid":{"rendered":"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?p=1071"},"modified":"2018-11-30T16:27:48","modified_gmt":"2018-11-30T16:27:48","slug":"latest-paper-has-just-been-published-in-nature-catalysis","status":"publish","type":"post","link":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?p=1071","title":{"rendered":"Latest paper has just been published in Nature Catalysis"},"content":{"rendered":"<p>The Micklefield Lab&#8217;s latest paper has just been published in <em>Nature Catalysis. <\/em>The paper<em>\u00a0<\/em>describes the discovery of a new biosynthetic\u00a0pathway, with a highly unusual carboxylase enzyme (MloH), producing a structurally unique antibiotic malonomycin.\u00a0The new findings might lead to the discovery of new antibiotics and may also provide new\u00a0ways of making antibiotics which are urgently needed to combat emerging drug-resistant pathogens.<\/p>\n<p><a href=\"http:\/\/dx.doi.org\/10.1038\/s41929-018-0178-2\">http:\/\/dx.doi.org\/10.1038\/s41929-018-0178-2<\/a><\/p>\n<p><a href=\"http:\/\/em.rdcu.be\/wf\/click?upn=lMZy1lernSJ7apc5DgYM8XiKXj7-2FQA8ZB-2FHEpmmqsgM-3D_kKLYQ91ZFOe6ryzRU3CXyppHwrrn5LyTOxQBvjscXceAeWy1IqmMZtgBfFKOHs0Zk4gZhaI4vRpdqPSdvfdAmOlpK5HAOoQ0ZEUP-2Bk6ADebd5xxBZQq-2FeycfkY2H1NQYmo1g9Q-2Fr9w5u9nZrwueqmcAmDYyu4RpBWWDZaRXcEWTVbs5obcUS-2FFuwLOo-2FA1IoRB3-2Fd8exF-2BUbJYtUx9WljpS82M0GwU3pM0tf3EOtPzAq2ExYt224uapeT5o3OBiu9Ar5Q9ipZ1qVYtL9hK3IUyRnc8i-2F9sicAU75L97JTxc-3D\">https:\/\/rdcu.be\/bbZ99<\/a><\/p>\n<p><a href=\"https:\/\/go.nature.com\/2r4Smbu\">https:\/\/go.nature.com\/2r4Smbu<\/a><\/p>\n<p><a href=\"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/wp-content\/uploads\/2018\/11\/Picture11.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1075\" src=\"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/wp-content\/uploads\/2018\/11\/Picture11.png\" alt=\"Picture1\" width=\"1020\" height=\"802\" srcset=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/wp-content\/uploads\/2018\/11\/Picture11.png 1020w, https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/wp-content\/uploads\/2018\/11\/Picture11-300x236.png 300w\" sizes=\"auto, (max-width: 1020px) 100vw, 1020px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Micklefield Lab&#8217;s latest paper has just been published in Nature Catalysis. The paper\u00a0describes the discovery of a new biosynthetic\u00a0pathway, with a highly unusual carboxylase enzyme (MloH), producing a structurally unique antibiotic malonomycin.\u00a0The new findings might lead to the discovery &hellip; <a href=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?p=1071\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1071","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/posts\/1071","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1071"}],"version-history":[{"count":3,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/posts\/1071\/revisions"}],"predecessor-version":[{"id":1160,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/posts\/1071\/revisions\/1160"}],"wp:attachment":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1071"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1071"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1071"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}