{"id":71,"date":"2012-08-22T21:10:27","date_gmt":"2012-08-22T20:10:27","guid":{"rendered":"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=71"},"modified":"2017-05-10T15:58:08","modified_gmt":"2017-05-10T14:58:08","slug":"neil-dixon","status":"publish","type":"page","link":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=71","title":{"rendered":"Dr. Neil Dixon"},"content":{"rendered":"<p>Neil completed his\u00a0BSc &amp; PhD at the University of Leeds.<\/p>\n<p><span style=\"text-decoration: underline;\">Publications:<\/span><\/p>\n<p><strong>Dual transcriptional-translational cascade permits cellular level tuneable expression control.\u00a0<\/strong>R. Morra, J. Shankar, C.J. Robinson, L. Butler, S. Halliwell, S. Hay, J. Micklefield, <strong>N. Dixon<\/strong> <em>Nucleic Acid Res.\u00a0<\/em><strong>2016,<\/strong><em> 44,\u00a0<\/em>e21 (<a href=\"http:\/\/dx.doi.org\/10.1093\/nar\/gkv912\">http:\/\/dx.doi.org\/10.1093\/nar\/gkv912<\/a>)<\/p>\n<p><strong>Rational Re-engineering of the Transcriptional Silencing PreQ1 Riboswitch.\u00a0<\/strong>M.-C. Wu, P.T. Lowe, C.J. Robinson, H.A. Vincent, <strong>N. Dixon<\/strong>, J. Leigh, J. Micklefield\u00a0<em>J. Am. Chem. Soc.<\/em><strong> 2015<\/strong> <em>137,\u00a0<\/em>9015-9021\u00a0(<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jacs.5b03405\">http:\/\/dx.doi.org\/10.1021\/jacs.5b03405<\/a>)<em>\u00a0<\/em><\/p>\n<p><strong>Orthogonal Riboswitches for tuneable co-expression in bacteria. N. Dixon,\u00a0<\/strong>C. Robinson, J.N. Duncan, T. Geerlings, S.P. Drummons and J. Micklefield\u00a0<em>Angew. Chem. INt. Ed.\u00a0<\/em><strong>2012<\/strong>, 51, 3620-3624. (<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201109106\/abstract\">http:\/\/dx.doi.org\/10.1002\/anie.201109106<\/a>)<\/p>\n<p><strong>Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues.\u00a0<\/strong>L. Chen, E. Cressina,\u00a0<strong>N. Dixon<\/strong>, K. Erixon, K. Agyei-Owusu, J. Micklefield, A.G. Smith, C. Abell and F.J. Leeper\u00a0<em>Org. Biomol. Chem.\u00a0<\/em><strong>2012<\/strong>, 10, 5924-5931. DOI: <a href=\"http:\/\/pubs.rsc.org\/en\/Content\/ArticleLanding\/2012\/OB\/c2ob07116a#!divAbstract\">10.1039\/c2ob07116a<\/a><\/p>\n<p><strong>Reengineering orthogonally selective riboswitches. N.Dixon,<\/strong> J. Duncan, T. Geerlings, M.S. Dunstan, D. Leys and J. Micklefield\u00a0<em>Proc. Natl. Acad. Sci. USA<\/em>\u00a0<strong>2010<\/strong>, 107, 2830-2835. (<a href=\"http:\/\/www.pnas.org\/content\/107\/7\/2830\">http:\/\/dx.doi.org\/10.1073\/pnas.0911209107<\/a>). Highlighted in\u00a0<em>Nature<\/em>\u00a0<strong>2010<\/strong>, 463, 591, spotlight in\u00a0<em>ACS Chemical Biology\u00a0<\/em>2010, 5, 349 and evaluated by Faculty1000.<\/p>\n<p><strong>Cellular targets of natural products.<\/strong>\u00a0<strong>N. Dixon<\/strong>, L.S. Wong, T. Geerlings and J. Micklefield Nat. Prod. Rep<strong> 2007<\/strong><em>, 24<\/em>, 1288-1310.\u00a0<span style=\"text-decoration: underline;\">Highlighted on front cover.<\/span> (<a href=\"http:\/\/pubs.rsc.org\/en\/Content\/ArticleLanding\/2007\/NP\/b616808f#!divAbstract\">http:\/\/dx.doi.org\/10.1039\/b616808f<\/a>)<\/p>\n<p><span style=\"text-decoration: underline;\">Patents:<\/span><\/p>\n<p><strong>N. Dixon<\/strong> and J. Micklefield &#8220;Riboswitch-regulated transgene expression systems&#8221; PCT INt. Appl. (2012), WO 2012153142. A2 20121115<\/p>\n<p><span style=\"text-decoration: underline;\">Conference contributions, refereed<\/span><\/p>\n<p>Orthogonal riboswitches as tools for controlling gene expression in bacteria.\u00a0<strong>N. Dixon<\/strong>, C.J. Robinson, J.N. Duncan, T. Geerlings, S.A. Lestari, J. Micklefield,\u00a0<em>Collection Symposium Series\u00a0<\/em>(<strong>2011<\/strong>), 12 (Chemistry of Nucleic Acid Components), 86-94<\/p>\n<p><span style=\"text-decoration: underline;\">Conference contributions, other (presenting author is underlined<\/span><\/p>\n<p><span style=\"text-decoration: underline;\">C.J. Robinson<\/span>, <strong>N. Dixon<\/strong>, J.N. Duncan, T. Geerlings,\u00a0M.-C. Wu,\u00a0P. Lowe, J. Micklefields, &#8220;Orthogonal Riboswitches As Tools for Controlling Gene Expression in Bacteria,&#8221; RNA 2012: The 17th Annual Meeting of the RNA Society, The University of Michigan, Ann Arbor, Mi, USA. May 29-Jun 2, 2012<\/p>\n<p><strong><span style=\"text-decoration: underline;\">N. Dixon<\/span><\/strong>, J. Micklefield\u00a0<em>et al.<\/em> Lecture at the 10th Annual RiboClub Meeting Sherbrooke, Canada 21-24th September 2009. New riboswitch-based tools for orthogonal genetic regulation<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>N. Dixon<\/strong><\/span>, J. Micklefield\u00a0<em>et al.<\/em> Lecture &amp; poster at the 13th Asian Chemical Congress Shanghai, China 14-16th September 2009. New riboswitch-based tools for orthogonal genetic regulation<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>N. Dixon<\/strong><\/span>, J. Micklefield\u00a0<em>et al.<\/em> Lecture at the Nucleic Acid-Chemical Biology Interface Meeting (Royal Society of Chemistry) 7-8th September 2009. New riboswitch-based tools for orthogonal genetic regulation<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>N. Dixon<\/strong><\/span>, J. Micklefield\u00a0<em>et al.<\/em> FEBS Advanced Lecture Course. Spetses, Greece, September 2008. Evolution vs. Design: New riboswitch based genetic circuitry.<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>N. Dixon<\/strong><\/span>, J. Micklefield\u00a0<em>et al.\u00a0<\/em>Lecture at the Nucleic Acid Group Meeting (RSC) Southampton July 2008. New riboswitch based genetic circuitry.<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>N. Dixon<\/strong><\/span>, J. Micklefield\u00a0<em>et al.\u00a0<\/em>Lecture at the BBSRC Selective Chemical Intervention in Biological Systems Conference Series October 2007. Co-evolution of small molecule responsive riboswitches.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neil completed his\u00a0BSc &amp; PhD at the University of Leeds. Publications: Dual transcriptional-translational cascade permits cellular level tuneable expression control.\u00a0R. Morra, J. Shankar, C.J. Robinson, L. Butler, S. Halliwell, S. Hay, J. Micklefield, N. Dixon Nucleic Acid Res.\u00a02016, 44,\u00a0e21 (http:\/\/dx.doi.org\/10.1093\/nar\/gkv912) &hellip; <a href=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=71\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-71","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/71","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=71"}],"version-history":[{"count":12,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/71\/revisions"}],"predecessor-version":[{"id":915,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/71\/revisions\/915"}],"wp:attachment":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=71"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}