{"id":526,"date":"2015-05-27T09:54:36","date_gmt":"2015-05-27T08:54:36","guid":{"rendered":"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=526"},"modified":"2017-05-10T16:18:09","modified_gmt":"2017-05-10T15:18:10","slug":"dr-gabriel-chukwu-uguru","status":"publish","type":"page","link":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=526","title":{"rendered":"Dr. Gabriel Chukwu Uguru"},"content":{"rendered":"<p>Gabriel achieved his PhD in Nigeria. He became a PDRA at the University of Strathclyde. He moved on to a PDRA position at the University of Leeds.<\/p>\n<p><span style=\"text-decoration: underline;\">Publications:<\/span><\/p>\n<p><strong>Active-site modifications of adenylation domains leads to hydrolysis of upstream nonribosomal peptidyl thioester intermediates.\u00a0G.C. Uguru<\/strong>,\u00a0C. Milne,\u00a0M. Borg, F. Flett, C.P. Smith and J. Micklefield\u00a0<em>J. Am. chem.<\/em>\u00a0Soc.<strong>\u00a02004<\/strong><em>, 126<\/em>, 5032-5033. (<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ja048778y\">http:\/\/dx.doi.org\/10.1021\/ja048778y<\/a>)<\/p>\n<p><span style=\"text-decoration: underline;\">Conference contributions, refereed:<\/span><\/p>\n<p>C.E. Milne, Z. Hojati,\u00a0L. Gordon, J. Jim, <strong>G. Uguru<\/strong>, C.P. Smith and J. Micklefield &#8220;Structure, biosynthetic origin and engineered biosynthesis of Calcium Dependent Antibiotic from Streptomyces Coelicolor&#8221;\u00a0<em>Abstr. Pap. Am. Chem.<\/em>\u00a0Soc.<strong>\u00a02003<\/strong><em>, 226<\/em>, ORGN-534.<\/p>\n<p><span style=\"text-decoration: underline;\">Conference contributions, other (presenting author is underlined):<\/span><\/p>\n<p><span style=\"text-decoration: underline;\">C. Milne<\/span>,\u00a0L. Gordon, Z. hojati, J. Jim, <strong>G. Uguru<\/strong>, C.P. Smith and J. Micklefield. &#8220;Structure, biosynthetic origin and engineered biosynthesis of calcium dependent antibiotics from\u00a0<em>Streptomyces Coelicolor.&#8221;<\/em>\u00a0<em>RSC Postgraduate Symposium on Organic and Medicinal Chemistry,\u00a0<\/em>Cambridge University, 9 Dec\u00a0<strong>2002.<\/strong>\u00a0(oral\/abstract).<\/p>\n<p><span style=\"text-decoration: underline;\">C. Milne<\/span>,\u00a0L. Gordon, Z. hojati, J. Jim, <strong>G. Uguru<\/strong>, C.P. Smith and J. Micklefield. &#8220;Structure, biosynthetic origin and engineered biosynthesis of calcium dependent antibiotics from\u00a0<em>Streptomyces Coelicolor.&#8221;<\/em>\u00a0<em>RSC Bio-organic Symposium<\/em>, St. Johns College, Cambridge, 27 Nov\u00a0<strong>2002<\/strong><strong>.<\/strong>\u00a0(oral\/abstract).<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>G. Uguru<\/strong><\/span>, F. Flett, J. Micklefield, C.P. Smith. &#8220;Alteration of the Adenylation domain specificities of CDA NRPS by site-directed mutagenesis&#8221;\u00a0<em>Abstracts of the 9th International Symposium on the genetics of industrial microorganisms (<\/em>GIM), Gyongju, Korea, 1-5 July,\u00a0<strong>2002<\/strong> pp.98<\/p>\n<p><span style=\"text-decoration: underline;\">J. Micklefield<\/span>, A.E. Hayes, Z. H. Najafabadi, <strong>G.C. Uguru<\/strong>,\u00a0J.M. Neary,\u00a0C. Milne, L. Gordon, J. Jim, M. Borg, F. Flett and C.P. Smith. &#8220;CDA biosynthesis: towards the engineered biosynthesis of novel lipopeptide antibiotics.&#8221;\u00a0<em>BBSRC Workshop on Natural Products Biology<\/em>, University of Warwick, 21-22 May\u00a0<strong>2001<\/strong>\u00a0(poster)<\/p>\n<p>J. Micklefield, A.E. Hayes, Z. H. Najafabadi, <strong>G.C. Uguru<\/strong>,\u00a0J.M. Neary,\u00a0C. Milne, L. Gordon, J. Jim,\u00a0M. Borg, F. Flett and\u00a0<span style=\"text-decoration: underline;\">C.P. Smith<\/span>. &#8220;Characterisation of the nonribosomal peptide synthetases and other key enzymes involved in CDA biosynthesis: Towards the engineered biosynthesis of novel lipopeptide antibiotics.&#8221;\u00a0<em>Conference on Streptomyces<\/em>, University of Warwick, Feb\u00a0<strong>2001<\/strong>. (Poster).<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gabriel achieved his PhD in Nigeria. He became a PDRA at the University of Strathclyde. He moved on to a PDRA position at the University of Leeds. Publications: Active-site modifications of adenylation domains leads to hydrolysis of upstream nonribosomal peptidyl &hellip; <a href=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=526\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-526","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/526","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=526"}],"version-history":[{"count":4,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/526\/revisions"}],"predecessor-version":[{"id":930,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/526\/revisions\/930"}],"wp:attachment":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=526"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}