{"id":510,"date":"2015-05-26T16:25:23","date_gmt":"2015-05-26T15:25:23","guid":{"rendered":"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=510"},"modified":"2016-04-13T15:25:24","modified_gmt":"2016-04-13T14:25:24","slug":"dr-adam-p-orourke","status":"publish","type":"page","link":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=510","title":{"rendered":"Dr. Adam P. O&#8217;Rourke"},"content":{"rendered":"<p><span style=\"text-decoration: underline;\">Publications:<\/span><\/p>\n<p><strong>Mixed-sequence pyrrolidine-amide oligonucleotide mimics: Boc(Z) synthesis and DNA\/RNA binding properties. <\/strong>R. Worthington, <strong>A. O&#8217;Rourke<\/strong>, J. Morral, T.H.S. Tan and J. Micklefield <em>Org. Biomol. Chem<\/em>.,<strong>\u00a02007<\/strong><em>, 5<\/em>, 249-259. (<a href=\"http:\/\/pubs.rsc.org\/en\/Content\/ArticleLanding\/2007\/OB\/B613386J#!divAbstract\">http:\/\/dx.doi.org\/10.1039\/b613386j<\/a>)<\/p>\n<p><strong>Homopolymeric pyrrolidine-amide oligonucleotide mimics: Fmoc-synthesis and DNA\/RNA binding properties.\u00a0<\/strong>T.H.S. Tan,\u00a0R. Worthington, <strong>A. O&#8217;Rourke<\/strong>, J. Morral, R.G. Pritchard and J. Micklefield\u00a0<em>Org. Biomol.<\/em>\u00a0Chem.,<strong>\u00a02007<\/strong><em>, 5<\/em>, 239-248. (<a href=\"http:\/\/pubs.rsc.org\/en\/Content\/ArticleLanding\/2007\/OB\/B613384N#!divAbstract\">http:\/\/dx.doi.org\/10.1039\/b613384n<\/a>)<\/p>\n<p>These two\u00a0<em>OBC<\/em>\u00a0papers were\u00a0highlighted on the front cover:\u00a0&#8220;Pyrrolidine amide oligonucleotide mimics (POM): Chemical biology solutions from zebrafish developmental biology through to high throughput DNA sequencing.&#8221;<\/p>\n<p><span style=\"text-decoration: underline;\">Conference contributions, refereed:<\/span><\/p>\n<p><strong>A.P. O&#8217;Rourke<\/strong>,\u00a0R.J. Worthington, J. Morral and J. Micklefield &#8220;Synthesis and UV hybridization studies of mixed-sequence pyrrolidine-amide oligonucleotide mimics (POM).&#8221;\u00a0<em>Abstr. Pap. Am. Chem.<\/em>\u00a0Soc.<strong>\u00a02005<\/strong><em>, 230<\/em>, ORGN-605.<\/p>\n<p><span style=\"text-decoration: underline;\">Conference contributions, other (presenting author is underlined)<\/span><\/p>\n<p><span style=\"text-decoration: underline;\">R. Worthington<\/span>, N. Bell, <strong>A. O&#8217;Rourke<\/strong>, J. Micklefield &#8220;Redesigning nature&#8217;s genetic material: pyrrolidine amide oligonucleotide mimics&#8221;\u00a0<em>RSC Bio-organic Chemistry Annual Meeting.\u00a0<\/em>MIB Manchester, 18 Dec\u00a0<strong>2006.<\/strong>\u00a0(Poster)<\/p>\n<p><span style=\"text-decoration: underline;\">R. Worthington<\/span>, <strong>A. O&#8217;Rourke<\/strong>, J. Micklefield &#8220;Synthesis and DNA\/RNA binding properties of mixed sequence pyrrolidine amide oligonucleotide mimics&#8221;\u00a0<em>RSC Nucleic Acids Forum<\/em>, MIB Manchester 7 July\u00a0<strong>2006.<\/strong>\u00a0(Poster).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Publications: Mixed-sequence pyrrolidine-amide oligonucleotide mimics: Boc(Z) synthesis and DNA\/RNA binding properties. R. Worthington, A. O&#8217;Rourke, J. Morral, T.H.S. Tan and J. Micklefield Org. Biomol. Chem.,\u00a02007, 5, 249-259. (http:\/\/dx.doi.org\/10.1039\/b613386j) Homopolymeric pyrrolidine-amide oligonucleotide mimics: Fmoc-synthesis and DNA\/RNA binding properties.\u00a0T.H.S. Tan,\u00a0R. Worthington, A. &hellip; <a href=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=510\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-510","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/510","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=510"}],"version-history":[{"count":4,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/510\/revisions"}],"predecessor-version":[{"id":771,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/510\/revisions\/771"}],"wp:attachment":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=510"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}