{"id":497,"date":"2015-05-26T15:36:05","date_gmt":"2015-05-26T14:36:05","guid":{"rendered":"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=497"},"modified":"2015-06-29T12:59:07","modified_gmt":"2015-06-29T11:59:07","slug":"dr-lyndsey-gordon","status":"publish","type":"page","link":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=497","title":{"rendered":"Dr. Lyndsey Gordon"},"content":{"rendered":"

Publications:<\/span><\/p>\n

An asparagine oxygenase (AsnO) and a 3-hydroxyasparaginyl phosphotransferase (HasP) are involved in the biosynthesis of calcium dependent lipopeptide antibiotics.\u00a0<\/strong>J. Neary,\u00a0A. Powell, L. Gordon<\/strong>, C. Milne, F. Flett, B. Wilkinson, C.P. Smith and J. Micklefield\u00a0Microbiology<\/em>\u00a02007<\/strong>, 153<\/em>, 768-776. (http:\/\/dx.doi.org\/10.1099\/mic.0.2006\/002725-0<\/a>)<\/p>\n

Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from\u00a0Streptomyces coelicolor<\/em><\/strong>. Z. Hojati, C. Milne, L. Gordon<\/strong>,\u00a0M. Borg, F. Flett, B. Wilkinson, P. J. Sidebottom, B.A.M. Rudd, M.A. Hayes, C.P. Smith and J. Micklefield\u00a0Chemistry & Biology<\/em>\u00a02002<\/strong>, 9<\/em>, 1175-1187. (http:\/\/dx.doi.org\/10.1016\/s1074-5521(02)00252-1<\/a>). Featured as the lead article and was illustrated on the fron cover “Chemobiosynthesis leads to new lipopeptide antibiotics”.<\/em>\u00a0This paper was also reviewed “New compounds by combining modern genomics and old-fashioned mutasynthesis”<\/em>\u00a0by Wohlleben, W.; Pelzer, S. Chemistry & Biology\u00a02002<\/strong>,\u00a09<\/em>, 1163<\/p>\n

Conference contributions, refereed:<\/span><\/p>\n

C.E. Milne, Z. Hojati, L. Gordon<\/strong>, J. Jim, G. Uguru, C.P. Smith and J. Micklefield “Structure, biosynthetic origin and engineered biosynthesis of Calcium Dependent Antibiotic from Streptomyces Coelicolor”\u00a0Abstr. Pap. Am. Chem.<\/em> Soc. 2003<\/strong>, 226<\/em>, ORGN-534.<\/p>\n

Conference contributions, other (presenting author is underlined):<\/span><\/p>\n

C. Milne<\/span>,\u00a0L. Gordon<\/strong>, Z. hojati, J. Jim, G. Uguru, C.P. Smith and J. Micklefield. “Structure, biosynthetic origin and engineered biosynthesis of calcium dependent antibiotics from\u00a0Streptomyces Coelicolor.”<\/em>\u00a0RSC Postgraduate Symposium on Organic and Medicinal Chemistry,\u00a0<\/em>Cambridge University, 9 Dec\u00a02002.<\/strong> (oral\/abstract).<\/p>\n

C. Milne<\/span>,\u00a0L. Gordon<\/strong>, Z. hojati, J. Jim, G. Uguru, C.P. Smith and J. Micklefield. “Structure, biosynthetic origin and engineered biosynthesis of calcium dependent antibiotics from\u00a0Streptomyces Coelicolor.”<\/em>\u00a0RSC Bio-organic Symposium<\/em>, St. Johns College, Cambridge, 27 Nov\u00a02002<\/strong>.<\/strong> (oral\/abstract).<\/p>\n

L. Gordon,<\/strong><\/span> Z. Hojati, C. Milne, B.A.M. Rudd, M. A. Hayes, J. Micklefield and C.P. Smith. “Characterisation of natural and engineered variants of calcium-dependent antibiotics of\u00a0Streptomyces coelicolor<\/em> and manipulation of the genes involved in its biosynthesis.”\u00a0Seventh international Conference on the Biotechnology of Microbial Natural Products (BMP) 2002,\u00a0<\/em>Honolulu, Hawaii, Oct 27-30,\u00a02002<\/strong>, pp. 35 (poster).<\/p>\n

J. Micklefield<\/span>, A.E. Hayes, Z. H. Najafabadi, G.C. Uguru,\u00a0J.M. Neary, C. Milne, L. Gordon<\/strong>, J. Jim,\u00a0M. Borg, F. Flett and C.P. Smith. “CDA biosynthesis: towards the engineered biosynthesis of novel lipopeptide antibiotics.”\u00a0BBSRC Workshop on Natural Products Biology<\/em>, University of Warwick, 21-22 May\u00a02001<\/strong>\u00a0(poster).<\/p>\n

J. Micklefield, A.E. Hayes, Z. H. ajafabadi, G.C. Uguru, J.M. Neary, C. Milne, L. Gordon<\/strong>, J. Jim,\u00a0M. Borg, F. Flett and\u00a0C.P. Smith<\/span>. “Characterisation of the nonribosomal peptide synthetases and other key enzymes involved in CDA biosynthesis: Towards the engineered biosynthesis of novel lipopeptide antibiotics.”\u00a0Conference on Streptomyces<\/em>, University of Warwick, Feb\u00a02001<\/strong>. (Poster).<\/p>\n","protected":false},"excerpt":{"rendered":"

Publications: An asparagine oxygenase (AsnO) and a 3-hydroxyasparaginyl phosphotransferase (HasP) are involved in the biosynthesis of calcium dependent lipopeptide antibiotics.\u00a0J. Neary,\u00a0A. Powell, L. Gordon, C. Milne, F. Flett, B. Wilkinson, C.P. Smith and J. Micklefield\u00a0Microbiology\u00a02007, 153, 768-776. (http:\/\/dx.doi.org\/10.1099\/mic.0.2006\/002725-0) Structure, biosynthetic … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-497","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/497","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=497"}],"version-history":[{"count":4,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/497\/revisions"}],"predecessor-version":[{"id":502,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/497\/revisions\/502"}],"wp:attachment":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=497"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}