{"id":484,"date":"2015-05-26T14:44:33","date_gmt":"2015-05-26T13:44:33","guid":{"rendered":"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=484"},"modified":"2015-06-29T11:18:45","modified_gmt":"2015-06-29T10:18:45","slug":"dr-amanda-jane-powell","status":"publish","type":"page","link":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=484","title":{"rendered":"Dr. Amanda Jane Powell"},"content":{"rendered":"<p><span style=\"text-decoration: underline;\">Publications:<\/span><\/p>\n<p><strong>Engineered biosynthesis of nonribosomal lipopeptide antibiotics with modified fatty acid side chains<\/strong>.\u00a0<strong>A. Powell<\/strong>, M. Borg, B. Amir-Heidari, J.M. Neary,\u00a0J. Thirlway, B. Wilkinson, C.P. Smith and J. Micklefield\u00a0<em>J. Am. Chem. Soc.<\/em>\u00a0<strong>2007<\/strong><em>, 129<\/em>, 15182-15191. Articles based on this paper were published in the\u00a0Daily Express, Chemistry &amp; Industry, Manchester Evening News\u00a0see below. (<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ja074331o\">http:\/\/dx.doi.org\/10.1021\/ja074331o<\/a>)<\/p>\n<p><strong>Precursor-directed biosynthesis of nonribosomal lipopeptides with modified glutamate residues.\u00a0A. Powell<\/strong>,\u00a0M. Al Nakeeb, B. Wilkinson and J. Micklefield\u00a0<em>Chem. Commun.<\/em>\u00a0<strong>2007<\/strong>, 2683-2685.\u00a0Highlighted on the front cover.\u00a0(<a href=\"http:\/\/pubs.rsc.org\/en\/Content\/ArticleLanding\/2007\/CC\/b706224a#!divAbstract\">http:\/\/dx.doi.org\/10.1039\/b706224a<\/a>)<\/p>\n<p><span style=\"color: #000000;\"><strong>An asparagine oxygenase (AsnO) and a 3-hydroxyasparaginyl phosphotransferase (HasP) are involved in the biosynthesis of calcium dependent lipopeptide antibiotics.\u00a0<\/strong>J. Neary,\u00a0<strong>A. Powell<\/strong>, L. Gordon, C. Milne, F. Flett, B. Wilkinson, C.P. Smith and J. Micklefield\u00a0<em>Microbiology<\/em>\u00a0<strong>2007<\/strong><em>, 153<\/em>, 768-776. (<a href=\"http:\/\/mic.sgmjournals.org\/content\/153\/3\/768\">http:\/\/dx.doi.org\/10.1099\/mic.0.2006\/002725-0<\/a>)<\/span><\/p>\n<p><strong>Biosynthesis of the (2<em>S<\/em>,3<em>R<\/em>)-3-methyl glutamate residue of nonribosomal lipopeptides.<\/strong>\u00a0C. Milne, <strong>A. Powell<\/strong>, J. Jim,\u00a0M. Al Nakeeb, C.P. Smith and J. Micklefield\u00a0<em>J. Am. Chem. Soc.\u00a0<\/em><strong>2006<\/strong><em>,\u00a0<\/em><em>128,<\/em>\u00a011250-11259. (<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ja062960c\">http:\/\/dx.doi.org\/10.1021\/ja062960c<\/a>)<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Publications: Engineered biosynthesis of nonribosomal lipopeptide antibiotics with modified fatty acid side chains.\u00a0A. Powell, M. Borg, B. Amir-Heidari, J.M. Neary,\u00a0J. Thirlway, B. Wilkinson, C.P. Smith and J. Micklefield\u00a0J. Am. Chem. Soc.\u00a02007, 129, 15182-15191. Articles based on this paper were published &hellip; <a href=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=484\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-484","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/484","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=484"}],"version-history":[{"count":4,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/484\/revisions"}],"predecessor-version":[{"id":563,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/484\/revisions\/563"}],"wp:attachment":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=484"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}