{"id":421,"date":"2015-05-19T13:05:29","date_gmt":"2015-05-19T12:05:29","guid":{"rendered":"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=421"},"modified":"2018-05-22T13:52:20","modified_gmt":"2018-05-22T12:52:20","slug":"dr-binuraj-menon","status":"publish","type":"page","link":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=421","title":{"rendered":"Dr. Binuraj Menon"},"content":{"rendered":"<p>Binuraj completed his\u00a0M.Sc. &amp; M. Tech in India and his PhD at the University of Manchester. He is currently a PDRA at the University of Manchester<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"text-decoration: underline;\">Publications<\/span>:<\/p>\n<ul>\n<li style=\"text-align: justify;\"><strong>Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase.<\/strong> M. R. Bennett, M. L. Thompson, S. A. Shepherd, M. S. Dunstan, A. J. Herbert, D. R. M. Smith, V. A. Cronin, <strong>B. R. K. Menon,<\/strong> C. Levy &amp; J. Micklefield Angew. Chem. Int. Ed. <strong>2018<\/strong> in press. (<a href=\"http:\/\/dx.doi.org\/10.1002\/anie.201805060\">http:\/\/dx.doi.org\/10.1002\/anie.201805060<\/a>)<\/li>\n<li style=\"text-align: justify;\"><strong>Development of Halogenase Enzymes for Use in Synthesis <\/strong>J. Latham, E. Brandenburger, S. A. Shepherd, <strong>B. R. K. Menon<\/strong> and J.Micklefield <em>Chem. Rev<\/em> <strong>2018<\/strong>, <em>118<\/em>, 232-269;\u00a0 (<a href=\"http:\/\/dx.doi.org\/10.1021\/acs.chemrev.7b00032\">http:\/\/dx.doi.org\/10.1021\/acs.chemrev.7b00032<\/a>)<\/li>\n<li style=\"text-align: justify;\"><strong>RadH: A Versatile Halogenase for Integration into Synthetic Pathways. B. R. K. Menon<\/strong>, E. Brandenburger, H. H. Sharif, U. Klemstein, M. F. Greaney, and J. Micklefield\u00a0<em>Angew. Chem. Int. Ed. <\/em><strong>2017<\/strong> in press (<a href=\"http:\/\/dx.doi.org\/10.1002\/anie.201706342\">http:\/\/dx.doi.org\/10.1002\/anie.201706342<\/a>)<\/li>\n<li style=\"text-align: justify;\"><strong>Development of Halogenase Enzymes for use in Synthesis.\u00a0<\/strong>Jonathan Latham, Eileen Brandenburger, Sarah A. Shepherd, <strong>Binuraj R. K. Menon<\/strong> and Jason Micklefield.\u00a0<em>American Chemical Society.\u00a0<\/em><strong>2017, <\/strong>(<a href=\"http:\/\/pubs.acs.org\/articlesonrequest\/AOR-XJV72fJWeGVD7wpMYnnX\">DOI: 10.1021\/acs.chemrev.7b00032<\/a>)<\/li>\n<li style=\"text-align: justify;\"><strong>Structure and Biocatalytic Scope of Thermophillic Flavin-Dependent Halogenase and Flavin Reductase Enzymes B. R. K. Menon<\/strong>, J. Latham, M. S. Dunstan, E. Brandenburger, U. Klemstein, S. A. Shepherd, C. Karthikeyan, M. F. Greaney, D. Leys and J. Micklefield* <em>Org. Biomol. Chem.<\/em> <strong>2016<\/strong>, <em>14<\/em>, 9354\u20139361<strong>.<\/strong> (<a href=\"http:\/\/dx.doi.org\/10.1039\/C6OB01861K\">http:\/\/dx.doi.org\/10.1039\/C6OB01861K<\/a>)<\/li>\n<li style=\"text-align: justify;\"><strong>Integrated Catalysis Opens New Arylation Pathways via Regiodivergent Enzymatic C-H Activation. <\/strong>J. Latham<em>, <\/em>J.-M. Henry, H. H. Sharif,\u00a0<strong>B. R. K. Menon<\/strong>, S. A. Shepherd,\u00a0 M. F. Greaney, J.Micklefield.\u00a0<em>Nature Commun. <\/em><strong>2016<\/strong>, 7, 11873 (<a href=\"http:\/\/dx.doi.org\/10.1038\/NCOMMS11873\">http:\/\/dx.doi.org\/10.1038\/NCOMMS11873<\/a>)<\/li>\n<li style=\"text-align: justify;\"><strong>A Structure-Guided Switch in the Regioselectivity<\/strong> <strong>of a Tryptophan Halogenase. <\/strong>S. A. Shepherd, <strong>B. R. K. Menon<\/strong>, H. Fisk, A.-W. Struck, C. Levy, D. Leys, J. Micklefield\u00a0<em>ChemBioChem<\/em> <strong>2016,\u00a0<\/strong>17, 9, p. 821\u2013824 \u00a0<a href=\"http:\/\/dx.doi.org\/10.1002\/cbic.201600051\">(<\/a><a href=\"http:\/\/dx.doi.org\/10.1002\/cbic.201600051\">http:\/\/dx.doi.org\/10.1002\/cbic.201600051<\/a><a href=\"http:\/\/dx.doi.org\/10.1002\/cbic.201600051\">)<\/a><\/li>\n<li style=\"text-align: justify;\"><strong>Extending the Biocatalytic Scope of Regiocomplementary Flavin-Dependent Halogenase Enzymes. S.A. Shepherd<\/strong>, C. Karthikeyan, J. Latham, A.-W. Struck, M. L. Thompson, B. Menon, C. Levy, D. Leys and J. Micklefield\u00a0<em>Chemical Science <\/em><strong>2015,\u00a0<\/strong><em>6, <\/em>3454-3460<em>\u00a0<\/em>(<a href=\"http:\/\/pubs.rsc.org\/en\/Content\/ArticleLanding\/2015\/SC\/C5SC00913H#!divAbstract\">http:\/\/dx.doi.org\/10.1039\/C5SC00913H<\/a>)<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Binuraj completed his\u00a0M.Sc. &amp; M. Tech in India and his PhD at the University of Manchester. He is currently a PDRA at the University of Manchester &nbsp; Publications: Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase. M. R. Bennett, M. L. &hellip; <a href=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=421\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-421","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/421","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=421"}],"version-history":[{"count":16,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/421\/revisions"}],"predecessor-version":[{"id":1017,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/421\/revisions\/1017"}],"wp:attachment":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=421"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}