{"id":213,"date":"2013-07-03T17:45:50","date_gmt":"2013-07-03T16:45:50","guid":{"rendered":"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=213"},"modified":"2016-01-25T10:17:59","modified_gmt":"2016-01-25T10:17:59","slug":"james-leigh","status":"publish","type":"page","link":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=213","title":{"rendered":"Dr. James Leigh"},"content":{"rendered":"<p><a href=\"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/wp-content\/uploads\/2013\/07\/Jimmy.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-thumbnail wp-image-214 alignleft\" title=\"Jimmy\" src=\"http:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/wp-content\/uploads\/2013\/07\/Jimmy-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/wp-content\/uploads\/2013\/07\/Jimmy-150x150.jpg 150w, https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/wp-content\/uploads\/2013\/07\/Jimmy.jpg 152w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><strong>James Leigh<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"text-decoration: underline;\">Publications:<\/span><\/p>\n<p><strong>Rational Re-engineering of the Transcriptional Silencing PreQ1 Riboswitch.\u00a0<\/strong>M.-C. Wu, P.T. Lowe,\u00a0C.J. Robinson, H.A. Vincent,\u00a0N. Dixon, <strong>J. Leigh<\/strong>, J. Micklefield\u00a0<em>J. Am. Chem. Soc.<\/em><strong> 2015<\/strong> <em>137,\u00a0<\/em>9015-9021\u00a0(<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jacs.5b03405\">http:\/\/dx.doi.org\/10.1021\/jacs.5b03405<\/a>)<em>\u00a0<\/em><\/p>\n<p><strong>Enzymatic Enantioselective Decarboxylative Protonation of Heteroaryl Malonates.\u00a0<\/strong>R. Lewin, M. Goodall, M.L. Thompson,\u00a0<strong>J. Leigh<\/strong>, M. Breuer, K. Baldenius and J. Micklefield\u00a0<em>Chem. Eur. J.,<\/em>\u00a0<strong>2015,<\/strong>\u00a0<em>17<\/em>, 6557-6563. DOI: <a href=\"http:\/\/www.chemeurope.com\/en\/publications\/781296\/enzymatic-enantioselective-decarboxylative-protonation-of-heteroaryl-malonates.html\">10.1002\/chem.201406014<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>James Leigh &nbsp; &nbsp; &nbsp; Publications: Rational Re-engineering of the Transcriptional Silencing PreQ1 Riboswitch.\u00a0M.-C. Wu, P.T. Lowe,\u00a0C.J. Robinson, H.A. Vincent,\u00a0N. Dixon, J. Leigh, J. Micklefield\u00a0J. Am. Chem. Soc. 2015 137,\u00a09015-9021\u00a0(http:\/\/dx.doi.org\/10.1021\/jacs.5b03405)\u00a0 Enzymatic Enantioselective Decarboxylative Protonation of Heteroaryl Malonates.\u00a0R. Lewin, M. Goodall, &hellip; <a href=\"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/?page_id=213\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-213","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/213","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=213"}],"version-history":[{"count":9,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/213\/revisions"}],"predecessor-version":[{"id":667,"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/213\/revisions\/667"}],"wp:attachment":[{"href":"https:\/\/www.micklefieldlab.chemistry.manchester.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=213"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}